Which medication is most commonly used to manage anaphylactic shock?

Epinephrine is the most commonly used medication to manage anaphylactic shock because it acts quickly to reverse the severe symptoms associated with this life-threatening allergic reaction. It works by constricting blood vessels, increasing blood pressure, and relaxing the muscles in the airways, allowing for easier breathing. Epinephrine's rapid onset and ability to counteract the effects of histamine released during anaphylaxis make it the first-line treatment in emergencies.

Other medications, such as antihistamines, may help relieve some of the symptoms of allergic reactions but do not address the underlying, life-threatening nature of anaphylactic shock. Similarly, while ephedrine and atropine can have their medical uses, they are not effective in managing anaphylaxis, as they do not provide the same rapid and comprehensive response that epinephrine does.